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BMJ Case Rep ; 14(3)2021 Mar 24.
Article in English | MEDLINE | ID: covidwho-1388475

ABSTRACT

SARS-CoV-2 infection has recently been related to a spectrum of hyper-inflammatory states in children. There is a striking similarity between these hyper-inflammatory states and Kawasaki disease (KD). We present an interesting case of KD recurrence in a 10-year-old child, who had previously developed KD at 4 years of age. His symptoms included fever, maculopapular rash and altered sensorium. Investigations showed noticeably elevated inflammatory markers, and an echocardiography revealed dilated coronary arteries. SARS-CoV-2 IgG antibodies were positive. The child responded dramatically to intravenous immunoglobulin and intravenous methylprednisolone. It is possible that SARS-CoV-2 infection triggered the recurrence of KD in this child who might have been genetically predisposed to KD.


Subject(s)
COVID-19/complications , Mucocutaneous Lymph Node Syndrome/etiology , Anti-Inflammatory Agents/therapeutic use , Antibodies, Viral/isolation & purification , COVID-19/therapy , Child , Echocardiography/methods , Humans , Immunoglobulins, Intravenous/administration & dosage , Male , Methylprednisolone/therapeutic use , Mucocutaneous Lymph Node Syndrome/therapy , Mucocutaneous Lymph Node Syndrome/virology , Recurrence , SARS-CoV-2 , Treatment Outcome
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